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1918-1919. An Epidemic Of `Spanish Flu` Spread Around The World. 1918-1919. An Epidemic Of Spanish Flu Spread Around The World. At Least 20 Million Died, Although Some Estimates Put The Final Toll At 50 Million. It`s Estimated That Between 20 Per Cent And 40 Per Cent Of The Entire World`s Population Became Sick