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acrylamide acrylic amide prop-2-enamide polyacrylamides precursor thickener flocculation agent starchy food carcinogenic polymer toxicity carcinogenicity maillard reaction heatox hazard skin irritant tumor initiator peripheral neuropathy dermatitis phytochemicals potato chips cigarettes smoking substance matter material compound component stuff reagent functional group synthesis production building block molecule molecular formula skeletal structural structure geometry ball stick 3d toxicant toxic toxin pollutant non-biodegradable