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flavoxanthin natural xanthophyll pigment all-trans-flavoxanthin e161a carotenediol golden-yellow yellow color food additive food adjuvants ingredient agent ins number coloring carotenoid tetraterpenes herbal phytochemical phytotherapy plant herb supplement biological activity nutrient nutraceutica dietary vitamin antioxidant anti-cancer healthy aging alternative medicine herbal molecule molecular formula skeletal structural structure biochemistry biomolecule bioactive biochemical 3d