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hexachlorobenzene perchlorobenzene hcb organochloride fungicide antimitotic fungal bunt banned persistent organic pollutants toxic fumes synthesis electrophilic aromatic substitution isomer agriculture fungus tilletia caries seed dressing carcinogen thyroid cancer photosensitivity teratogenic bioaccumulation aquatic organisms environment environmental anthropogenic biodegradation biomagnification biomagnify pollutant pollution non-biodegradable organic poison toxicant toxic toxicity toxin toxicology poisoning danger hazard harmful bane carcinogenicity carcinogenic 3d