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adenine guanine cytosine thiamine adenine guanine cytosine thymine dna bases nucleotides base pairs genetic code structure sequence a-t pairing g-c nitrogenous double helix nucleic acids material deoxyribonucleic acid replication molecular biology gene expression information complementary backbone genetics transcription translation genome rna purines pyrimidines strands hydrogen bonds molecules synthesis nucleotide pairing rules heredity cellular function chromosomes research mutations diversity biochemical reactions encoding polymerase rna structure